GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs10935120 | 1 | rs7374325 | chr3:134275601 | ANAPC13 | chr3:134196547-134204865:- | 0.5 | 7.97 | 1.89E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs7374325 | chr3:134275601 | CEP63 | chr3:134204575-134293852:+ | 0.24 | 4.09 | 5.33E-5 | Height |
| BLCA | cis | rs73201462 | 1 | rs7374952 | chr3:128001367 | EEFSEC | chr3:127872313-128127488:+ | -0.33 | -3.82 | 0.000153 | Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio |
| BLCA | cis | rs739310 | 1 | rs739310 | chr22:27051299 | ASPHD2 | chr22:26825280-26840978:+ | -0.28 | -4.57 | 6.53E-6 | Obesity-related traits |
| BLCA | cis | rs302668 | 1 | rs7395213 | chr11:87869579 | RAB38 | chr11:87846431-87908599:- | -0.24 | -4.15 | 4.09E-5 | Frontotemporal dementia |
| BLCA | cis | rs6430585 | 1 | rs73958618 | chr2:136500475 | DARS | chr2:136664254-136743222:- | 0.27 | 4.51 | 8.61E-6 | Corneal structure |
| BLCA | cis | rs7224737 | 1 | rs739637 | chr17:40280944 | DHX58 | chr17:40253422-40264751:- | -0.25 | -4.56 | 6.82E-6 | Fibrinogen levels |
| BLCA | cis | rs9910950 | 1 | rs73992250 | chr17:64132167 | AXIN2 | chr17:63524685-63637183:- | 0.56 | 4.92 | 1.3E-6 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs9910950 | 1 | rs73992258 | chr17:64165083 | AXIN2 | chr17:63524685-63637183:- | 0.53 | 4.6 | 5.8E-6 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs9910950 | 1 | rs73992265 | chr17:64181796 | AXIN2 | chr17:63524685-63637183:- | 0.53 | 4.51 | 8.77E-6 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs9910950 | 1 | rs73992267 | chr17:64183713 | AXIN2 | chr17:63524685-63637183:- | 0.53 | 4.5 | 8.9E-6 | Presence of antiphospholipid antibodies |
| BLCA | cis | rs7404095 | 1 | rs7404095 | chr16:23864590 | CHP2 | chr16:23765948-23770256:+ | 0.22 | 4.06 | 5.94E-5 | Ulcerative colitis;Inflammatory bowel disease |
| BLCA | cis | rs9894429 | 1 | rs7406003 | chr17:79597597 | TSPAN10 | chr17:79609349-79615778:+ | 0.49 | 8.59 | 2.28E-16 | Eye color traits |
| BLCA | cis | rs882367 | 1 | rs740755 | chr17:59496797 | C17orf82 | chr17:59489112-59490641:+ | -0.21 | -4.09 | 5.22E-5 | Sitting height ratio |
| BLCA | cis | rs4494548 | 1 | rs74209810 | chr16:20402466 | C16orf88 | chr16:19717676-19729492:- | -0.39 | -3.85 | 0.000136 | Urinary uromodulin levels |